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課程名稱 |
藥物分析（一）
Pharmaceutical Analysis (I) |
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開課學期 |
109-1 |
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授課對象 |
醫學院 藥學系 |
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授課教師 |
郭錦樺 |
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課號 |
PHARM4023 |
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課程識別碼 |
403 43110 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期四3,4(10:20~12:10) |
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上課地點 |
基醫304 |
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備註 |
與余秀瑛、忻凌偉、許麗卿、張嘉銓、張琳巧合授
總人數上限：70人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1091PHARM4023_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
The quality of a product may deviate from the standard required, but in carrying out an analysis one also has to be certain that the quality of the analysis itself is of the standard required. Quality control is integral to all modern industrial processes, and the pharmaceutical industry is no exception. Testing a pharmaceutical product involves chemical, physical and sometimes microbiological analyses. This course covers general used techniques for quality control of pharmaceutical products. |
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課程目標 |
Understand how to use various analytical approaches for identification and quantification of active pharmaceutical ingradient and the related impurities. |
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課程要求 |
Students in this class must finish the course of Analytical chemistry. |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
1. Pharmaceutical Analysis, 2ed., 2005. David G. Watson
2. Jenkin’s Quantitative Pharmaceutical Chemistry, 7th ed., 1977. A. M. Knevel, F. E. DiGangi
3. USP 30/NF 25, 2007
4. 中華藥典第六版, 2006
5. Reminton: The Science and Practice of Pharmacy (Chapters 32 and 33), 20th ed., 2000; (Chapters 33 and 34), 21st ed., 2006 |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/17 |
Introduction |
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第2週 |
9/24 |
Chromatographic Theory |
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第3週 |
10/01 |
中秋節 |
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第4週 |
10/08 |
HPLC |
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第5週 |
10/15 |
HPLC |
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第6週 |
10/22 |
Column Chromatography, TLC, Paper Chromatography |
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第7週 |
10/29 |
GC |
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第8週 |
11/05 |
Capillary Electrophoresis |
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第9週 |
11/12 |
Analytical Method Validation |
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第10週 |
11/19 |
期中考(基醫 301) |
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第11週 |
11/26 |
Nonaqueous Titrimetry, AAS, AES, ICP |
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第12週 |
12/03 |
Extraction Methods |
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第13週 |
12/10 |
Potentiometry and Water Determinations |
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第14週 |
12/17 |
Constants of Fats, Fatty Oils, Waxes |
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第15週 |
12/24 |
Assays of Volatile Oils |
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第16週 |
12/31 |
Methods used in the quality control of biologic drugs |
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第17週 |
1/07 |
The Value of Pharmaceutical Analysis in the New Drug Approval Process |
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第18週 |
01/14 |
期末考(基醫 301) |
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